| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1F |
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| Ligand | BDBM50156410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302837 (CHEMBL827882) |
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| Ki | 3.9±n/a nM |
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| Citation |  Zhang, D; Kohlman, D; Krushinski, J; Liang, S; Ying, BP; Reilly, JE; Dinn, SR; Wainscott, DB; Nutter, S; Gough, W; Nelson, DL; Schaus, JM; Xu, YC Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. Bioorg Med Chem Lett14:6011-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1F |
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| Name: | 5-hydroxytryptamine receptor 1F |
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| Synonyms: | 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | 5-HT1F HTR1F HUMAN::P30939 |
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| Residue: | 366 |
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| Sequence: | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
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| BDBM50156410 |
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| n/a |
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| Name | BDBM50156410 |
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| Synonyms: | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indazol-5-yl]-benzamide | CHEMBL184597 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21FN4O |
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| Mol. Mass. | 352.4053 |
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| SMILES | CN1CCC(CC1)c1n[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12 |
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| Structure | 
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