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TargetBradykinin B1 receptor
LigandBDBM50156451
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303697
Ki 0.02±n/a nM
Citation Su DSMarkowitz MKMurphy KLWan BLZrada MMHarrell CMO'Malley SSHess JFRansom RWChang RSWallace MARaab CEDean DCPettibone DJFreidinger RMBock MG Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies. Bioorg Med Chem Lett 14:6045-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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  Blast E-value cutoff:
BDBM50156451
n/a
NameBDBM50156451
Synonyms:2-[(R)-7-Chloro-1-(naphthalene-2-sulfonyl)-3-oxo-1,2,3,4-tetrahydro-quinoxalin-2-yl]-N-{2-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-phenyl]-ethyl}-acetamide | CHEMBL185693
TypeSmall organic molecule
Emp. Form.C32H30ClN5O4S
Mol. Mass.616.13
SMILESCN1CCN=C1c1ccc(CCNC(=O)C[C@H]2N(c3cc(Cl)ccc3NC2=O)S(=O)(=O)c2ccc3ccccc3c2)cc1 |c:4|
Structure
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