| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50156446 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302733 (CHEMBL838681) |
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| Ki | 0.5±n/a nM |
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| Citation |  Su, DS; Markowitz, MK; Murphy, KL; Wan, BL; Zrada, MM; Harrell, CM; O'Malley, SS; Hess, JF; Ransom, RW; Chang, RS; Wallace, MA; Raab, CE; Dean, DC; Pettibone, DJ; Freidinger, RM; Bock, MG Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies. Bioorg Med Chem Lett14:6045-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | BDKRB1 | BKRB1_CANLF | Bradykinin B1 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39530.03 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_662797 |
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| Residue: | 350 |
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| Sequence: | MASRAPLELLPLNRSQLSPPNATTCDDAPEAWDLLHRVLPSVIIIICVCGLLGNLLVLAV
LLRPRRRLNVAEMYLANLAASDLVFVLGLPFWAANISNQFRWPFGGLLCRLVNGVIKANL
FISIFLVVAISRDRYRALVHPMATRRRRQARATCVLIWVAGSLLSVPTFLFRSIEAVPEL
NNDSACVLLHPPGAWHVARMVELNVLGFLLPLAAIVFFNCHILASLRGRPEVRGARCGGP
PDGRTTALILTFVAAFLVCWTPYHFFAFLEFLTQVQVVRGCFWENFKDLGLQYASFFAFI
NSCLNPVIYVFVGRLFRTRVWDLFKQCAPRRPPAVSWSHRKRVLQLFWQN
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| BDBM50156446 |
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| n/a |
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| Name | BDBM50156446 |
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| Synonyms: | CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-yl)-phenyl]-ethyl}-2-[(R)-1-(naphthalene-2-sulfonyl)-3-oxo-1,2,3,4-tetrahydro-quinoxalin-2-yl]-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H29N5O4S |
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| Mol. Mass. | 567.658 |
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| SMILES | O=C(C[C@H]1N(c2ccccc2NC1=O)S(=O)(=O)c1ccc2ccccc2c1)NCCc1ccc(cc1)C1=NCCN1 |t:41| |
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| Structure | 
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