Reaction Details |
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Target | Tubulin beta chain [1-43] |
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Ligand | BDBM50156486 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_311631 (CHEMBL833941) |
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IC50 | 30000±n/a nM |
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Citation | Kim, S; Park, JH; Koo, SY; Kim, JI; Kim, MH; Kim, JE; Jo, K; Choi, HG; Lee, SB; Jung, SH Novel diarylsulfonylurea derivatives as potent antimitotic agents. Bioorg Med Chem Lett14:6075-8 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Tubulin beta chain [1-43] |
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Name: | Tubulin beta chain [1-43] |
Synonyms: | Beta tubulin | TBB_LEIME |
Type: | PROTEIN |
Mol. Mass.: | 4652.47 |
Organism: | Leishmania donovani |
Description: | ChEMBL_311916 |
Residue: | 43 |
Sequence: | MREIVSCQAGQCGNQIGSKFWEVIADEHGVDPTGSYQGDSDLQ
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BDBM50156486 |
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n/a |
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Name | BDBM50156486 |
Synonyms: | 5-((S)-2-Oxo-4-phenyl-imidazolidine-1-sulfonyl)-2,3-dihydro-indole-1-carboxylic acid 2-(4-methyl-piperazin-1-yl)-ethyl ester | CHEMBL364096 |
Type | Small organic molecule |
Emp. Form. | C25H31N5O5S |
Mol. Mass. | 513.609 |
SMILES | CN1CCN(CCOC(=O)N2CCc3cc(ccc23)S(=O)(=O)N2C[C@@H](NC2=O)c2ccccc2)CC1 |
Structure |
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