| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50156850 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_429753 (CHEMBL914453) |
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| IC50 | >10000±n/a nM |
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| Citation |  Fonquerna, S; Miralpeix, M; Pagès, L; Puig, C; Cardús, A; Antón, F; Cárdenas, A; Vilella, D; Aparici, M; Calaf, E; Prieto, J; Gras, J; Huerta, JM; Warrellow, G; Beleta, J; Ryder, H Synthesis and structure-activity relationships of novel histamine H1 antagonists: indolylpiperidinyl benzoic acid derivatives. J Med Chem47:6326-37 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50156850 |
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| n/a |
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| Name | BDBM50156850 |
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| Synonyms: | 2-{2-[4-(1-allyl-1H-indol-3-yl)piperidin-1-yl]ethoxy}-benzoic acid | CHEMBL221463 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28N2O3 |
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| Mol. Mass. | 404.5014 |
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| SMILES | OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(CC=C)c2ccccc12 |
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| Structure | 
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