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TargetKallikrein-1 (KLK1)
LigandBDBM50157089
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302558
Ki 379±n/a nM
Citation Bruncko MMcClellan WJWendt MDSauer DRGeyer ADalton CRKaminski MAWeitzberg MGong JDellaria JFMantei RZhao XNienaber VLStewart KKlinghofer VBouska JRockway TWGiranda VL Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties. Bioorg Med Chem Lett 15:93-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein-1 (KLK1)
Name:Kallikrein 1
Synonyms:Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein
Type:Enzyme
Mol. Mass.:28874.69
Organism:Homo sapiens (Human)
Description:P06870
Residue:262
Sequence:
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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  Blast E-value cutoff:
BDBM50157089
n/a
NameBDBM50157089
Synonyms:8-Bromo-6-(2-phenyl-cyclopropyl)-naphthalene-2-carboxamidine | CHEMBL181599
TypeSmall organic molecule
Emp. Form.C20H17BrN2
Mol. Mass.365.266
SMILESNC(=N)c1ccc2cc(cc(Br)c2c1)C1CC1c1ccccc1
Structure
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