| Reaction Details |
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 | Report a problem with these data |
| Target | Trypsin |
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| Ligand | BDBM50157089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302473 (CHEMBL826338) |
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| Ki | 334±n/a nM |
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| Citation |  Bruncko, M; McClellan, WJ; Wendt, MD; Sauer, DR; Geyer, A; Dalton, CR; Kaminski, MA; Weitzberg, M; Gong, J; Dellaria, JF; Mantei, R; Zhao, X; Nienaber, VL; Stewart, K; Klinghofer, V; Bouska, J; Rockway, TW; Giranda, VL Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties. Bioorg Med Chem Lett15:93-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trypsin |
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| Name: | Trypsin |
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| Synonyms: | TRYP_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24411.24 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_1450738 |
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| Residue: | 231 |
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| Sequence: | FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGE
HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA
GTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDS
CQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
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|
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| BDBM50157089 |
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| n/a |
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| Name | BDBM50157089 |
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| Synonyms: | 8-Bromo-6-(2-phenyl-cyclopropyl)-naphthalene-2-carboxamidine | CHEMBL181599 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17BrN2 |
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| Mol. Mass. | 365.266 |
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| SMILES | NC(=N)c1ccc2cc(cc(Br)c2c1)C1CC1c1ccccc1 |
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| Structure | 
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