Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50157216 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_305393 (CHEMBL833043) |
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IC50 | 10000±n/a nM |
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Citation | Garino, C; Bihel, F; Pietrancosta, N; Laras, Y; Quéléver, G; Woo, I; Klein, P; Bain, J; Boucher, JL; Kraus, JL New 2-bromomethyl-8-substituted-benzo[c]chromen-6-ones. Synthesis and biological properties. Bioorg Med Chem Lett15:135-8 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50157216 |
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n/a |
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Name | BDBM50157216 |
Synonyms: | 2-Bromomethyl-8-nitro-benzo[c]chromen-6-one | CHEMBL369126 |
Type | Small organic molecule |
Emp. Form. | C14H8BrNO4 |
Mol. Mass. | 334.122 |
SMILES | [O-][N+](=O)c1ccc2c3cc(CBr)ccc3oc(=O)c2c1 |
Structure |
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