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TargetBradykinin B1 receptor
LigandBDBM50157515
Substrate/Competitorn/a
Meas. Tech.ChEMBL_429983
IC50 2.4±n/a nM
Citation Kuduk SDNg CFeng DMWai JMChang RSHarrell CMMurphy KLRansom RWReiss DIvarsson MMason GBoyce STang CPrueksaritanont TFreidinger RMPettibone DJBock MG 2,3-diaminopyridine bradykinin B1 receptor antagonists. J Med Chem 47:6439-42 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39519.62
Organism:Oryctolagus cuniculus
Description:ChEMBL_796432
Residue:352
Sequence:
MASQGPLELQPSNQSQLAPPNATSCSGAPDAWDLLHRLLPTFIIAIFTLGLLGNSFVLSV
FLLARRRLSVAEIYLANLAASDLVFVLGLPFWAENVRNQFDWPFGAALCRIVNGVIKANL
FISIFLVVAISQDRYSVLVHPMASRRGRRRRQAQATCALIWLAGGLLSTPTFVLRSVRAV
PELNVSACILLLPHEAWHWLRMVELNLLGFLLPLAAILFFNCHILASLRRRGERVPSRCG
GPRDSKSTALILTLVASFLVCWAPYHFFAFLECLWQVHAIGGCFWEEFTDLGLQLSNFSA
FVNSCLNPVIYVFVGRLFRTKVWELCQQCSPRSLAPVSSSRRKEMLWGFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50157515
n/a
NameBDBM50157515
Synonyms:4'-{(R)-1-[4-chloro-3-(2-cyano-acetylamino)-pyridin-2-ylamino]-ethyl}-3-fluoro-biphenyl-2-carboxylic acid methyl ester | CHEMBL225607
TypeSmall organic molecule
Emp. Form.C24H20ClFN4O3
Mol. Mass.466.892
SMILESCOC(=O)c1c(F)cccc1-c1ccc(cc1)[C@@H](C)Nc1nccc(Cl)c1NC(=O)CC#N |r|
Structure
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