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TargetBDKRB1
LigandBDBM50157513
Substrate/Competitorn/a
Meas. Tech.ChEMBL_429981
Ki 35.7±n/a nM
Citation Kuduk SDNg CFeng DMWai JMChang RSHarrell CMMurphy KLRansom RWReiss DIvarsson MMason GBoyce STang CPrueksaritanont TFreidinger RMPettibone DJBock MG 2,3-diaminopyridine bradykinin B1 receptor antagonists. J Med Chem 47:6439-42 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
BDKRB1
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1R | BK-1 receptor | KB1 | Kinin B1 receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:38389.97
Organism:RAT
Description:B1 BRADYKININ BDKRB1 RAT::P97583
Residue:337
Sequence:
MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSF
FLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLC
RVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSI
PTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLR
GQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEIT
DLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50157513
n/a
NameBDBM50157513
Synonyms:3-chloro-4'-{(R)-1-[4-chloro-3-(2-cyano-acetylamino)-pyridin-2-ylamino]-ethyl}-biphenyl-2-carboxylic acid methyl ester | CHEMBL221998
TypeSmall organic molecule
Emp. Form.C24H20Cl2N4O3
Mol. Mass.483.347
SMILESCOC(=O)c1c(Cl)cccc1-c1ccc(cc1)[C@@H](C)Nc1nccc(Cl)c1NC(=O)CC#N |r|
Structure
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