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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Androgen receptor | ||
| Ligand | BDBM50157826 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_317562 (CHEMBL825228) | ||
| Ki | 0.5±n/a nM | ||
| Citation |  Salvati, ME; Balog, A; Shan, W; Wei, DD; Pickering, D; Attar, RM; Geng, J; Rizzo, CA; Gottardis, MM; Weinmann, R; Krystek, SR; Sack, J; An, Y; Kish, K Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists. Bioorg Med Chem Lett15:271-6 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Androgen receptor | |||
| Name: | Androgen receptor | ||
| Synonyms: | ANDR_HUMAN | AR | Androgen Receptor | Androgen receptor (AR) | Androgen receptor/Baculoviral IAP repeat-containing protein 2 | DHTR | Dihydrotestosterone receptor | NR3C4 | Nuclear receptor subfamily 3 group C member 4 | ||
| Type: | Receptor | ||
| Mol. Mass.: | 99185.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | CHO cells were stably transfected with human AR gene. | ||
| Residue: | 920 | ||
| Sequence: |
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| BDBM50157826 | |||
| n/a | |||
| Name | BDBM50157826 | ||
| Synonyms: | (2S,6R)-4-(4-Nitro-naphthalen-1-yl)-4-aza-tricyclo[5.2.2.0*2,6*]undec-8-ene-3,5-dione | CHEMBL361445 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H16N2O4 | ||
| Mol. Mass. | 348.352 | ||
| SMILES | Oc1c2C3CCC(C=C3)c2c(O)n1-c1ccc([N+]([O-])=O)c2ccccc12 |c:7,THB:10:9:7.8:4.5,(.45,2.28,;-.79,1.39,;-2.24,1.86,;-3.71,2.32,;-4.12,3.9,;-4.98,2.62,;-4.64,1.11,;-6.17,.83,;-5.2,2.02,;-3.15,.6,;-2.24,-.63,;-2.72,-2.1,;-.79,-.16,;.54,-.93,;.54,-2.47,;1.86,-3.23,;3.19,-2.47,;4.53,-3.23,;4.53,-4.76,;5.83,-2.48,;3.19,-.93,;4.53,-.16,;4.53,1.39,;3.17,2.14,;1.86,1.39,;1.86,-.16,)| | ||
| Structure | 
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