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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50159076
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303755
Ki 2.2±n/a nM
Citation Trapani GLaquintana VDenora NTrapani ALopedota ALatrofa AFranco MSerra MPisu MGFloris ISanna EBiggio GLiso G Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands. J Med Chem 48:292-305 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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BDBM50159076
n/a
NameBDBM50159076
Synonyms:CHEMBL180279 | N-Butyl-2-(6,8-dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N-methyl-acetamide
TypeSmall organic molecule
Emp. Form.C20H21Cl2N3O
Mol. Mass.390.306
SMILESCCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1
Structure
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