| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50159924 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303727 (CHEMBL829062) |
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| Ki | 45±n/a nM |
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| Citation |  Palin, R; Barn, DR; Clark, JK; Cottney, JE; Cowley, PM; Crockatt, M; Evans, L; Feilden, H; Goodwin, RR; Griekspoor, F; Grove, SJ; Houghton, AK; Jones, PS; Morphy, RJ; Smith, AR; Sundaram, H; Vrolijk, D; Weston, MA; Wishart, G; Wren, P Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists. Bioorg Med Chem Lett15:589-93 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50159924 |
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| n/a |
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| Name | BDBM50159924 |
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| Synonyms: | 1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-pentyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one | CHEMBL183323 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30ClN3O3 |
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| Mol. Mass. | 443.966 |
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| SMILES | CCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O |
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| Structure | 
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