| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 1 |
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| Ligand | BDBM50129656 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305881 (CHEMBL832744) |
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| IC50 | 620±n/a nM |
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| Citation |  Luo, QL; Li, JY; Liu, ZY; Chen, LL; Li, J; Ye, QZ; Nan, FJ Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffold. Bioorg Med Chem Lett15:635-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 1 |
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| Name: | Methionine aminopeptidase 1 |
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| Synonyms: | MAP 1 | MAP1 | MAP1_YEAST | MetAP 1 | Peptidase M 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43382.92 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_10701 |
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| Residue: | 387 |
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| Sequence: | MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYK
AHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQR
NDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYP
SPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGEN
ISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFF
HCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHT
LLVTEHGVEILTARNKKSPGGPRQRIK
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| BDBM50129656 |
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| n/a |
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| Name | BDBM50129656 |
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| Synonyms: | 3-Hexanoylamino-pyridine-2-carboxylic acid thiazol-2-ylamide | CHEMBL313650 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N4O2S |
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| Mol. Mass. | 318.394 |
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| SMILES | CCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1 |
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| Structure | 
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