| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50160824 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_310481 (CHEMBL834425) |
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| EC50 | 11±n/a nM |
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| Citation |  Sawa, M; Mizuno, K; Harada, H; Tateishi, H; Arai, Y; Suzuki, S; Oue, M; Tsujiuchi, H; Furutani, Y; Kato, S Tryptamine-based human beta3-adrenergic receptor agonists. Part 3: improved oral bioavailability via modification of the sulfonamide moiety. Bioorg Med Chem Lett15:1061-4 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50160824 |
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| n/a |
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| Name | BDBM50160824 |
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| Synonyms: | CHEMBL181603 | Methanesulfonic acid 3-{(R)-2-[(R)-2-hydroxy-2-(3-pent-2-enylamino-phenyl)-ethylamino]-propyl}-1H-indol-7-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N3O4S |
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| Mol. Mass. | 471.612 |
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| SMILES | CC\C=C\CNc1cccc(c1)[C@@H](O)CN[C@H](C)Cc1c[nH]c2c(OS(C)(=O)=O)cccc12 |
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| Structure | 
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