| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
|---|
| Ligand | BDBM50160914 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302705 (CHEMBL839577) |
|---|
| Ki | 1200±n/a nM |
|---|
| Citation |  Ducharme, Y; Blouin, M; Carrière, MC; Chateauneuf, A; Côté, B; Denis, D; Frenette, R; Greig, G; Kargman, S; Lamontagne, S; Martins, E; Nantel, F; O'Neill, G; Sawyer, N; Metters, KM; Friesen, RW 2,3-Diarylthiophenes as selective EP1 receptor antagonists. Bioorg Med Chem Lett15:1155-60 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thromboxane A2 receptor |
|---|
| Name: | Thromboxane A2 receptor |
|---|
| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
|---|
| Type: | Enyzme |
|---|
| Mol. Mass.: | 37445.28 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21731 |
|---|
| Residue: | 343 |
|---|
| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
|
|
|
|---|
| BDBM50160914 |
|---|
| n/a |
|---|
| Name | BDBM50160914 |
|---|
| Synonyms: | 3-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-N-(1-pyridin-3-yl-ethyl)-benzamide | CHEMBL360592 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H25ClN2O2S |
|---|
| Mol. Mass. | 525.06 |
|---|
| SMILES | CC(NC(=O)c1cccc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)c1cccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
