| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50160908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302705 (CHEMBL839577) |
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| Ki | 360±n/a nM |
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| Citation |  Ducharme, Y; Blouin, M; Carrière, MC; Chateauneuf, A; Côté, B; Denis, D; Frenette, R; Greig, G; Kargman, S; Lamontagne, S; Martins, E; Nantel, F; O'Neill, G; Sawyer, N; Metters, KM; Friesen, RW 2,3-Diarylthiophenes as selective EP1 receptor antagonists. Bioorg Med Chem Lett15:1155-60 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50160908 |
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| n/a |
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| Name | BDBM50160908 |
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| Synonyms: | CHEMBL182623 | {5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-hydroxy-acetonitrile |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17ClN2O2S |
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| Mol. Mass. | 432.922 |
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| SMILES | OC(C#N)c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1 |
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| Structure | 
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