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TargetProstaglandin E2 receptor EP1 subtype (EP1)
LigandBDBM50160909
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302785
Ki 4±n/a nM
Citation Ducharme YBlouin MCarrière MCChateauneuf ACôté BDenis DFrenette RGreig GKargman SLamontagne SMartins ENantel FO'Neill GSawyer NMetters KMFriesen RW 2,3-Diarylthiophenes as selective EP1 receptor antagonists. Bioorg Med Chem Lett 15:1155-60 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP1 subtype (EP1)
Name:Prostaglandin E2 receptor
Synonyms:PGE receptor, EP1 subtype | Prostaglandin E2 receptor EP1 subtype | Prostanoid EP1 receptor
Type:Enzyme
Mol. Mass.:41834.57
Organism:Homo sapiens (Human)
Description:P34995
Residue:402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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  Blast E-value cutoff:
BDBM50160909
n/a
NameBDBM50160909
Synonyms:1-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-2,2,2-trifluoro-ethane-1,1-diol | CHEMBL185346
TypeSmall organic molecule
Emp. Form.C24H17ClF3NO3S
Mol. Mass.491.91
SMILESOC(O)(c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)C(F)(F)F
Structure
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