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TargetProstanoid TP receptor
LigandBDBM50160909
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302705
Ki 220±n/a nM
Citation Ducharme YBlouin MCarrière MCChateauneuf ACôté BDenis DFrenette RGreig GKargman SLamontagne SMartins ENantel FO'Neill GSawyer NMetters KMFriesen RW 2,3-Diarylthiophenes as selective EP1 receptor antagonists. Bioorg Med Chem Lett 15:1155-60 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid TP receptor
Name:Thromboxane A2 receptor
Synonyms:TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50160909
n/a
NameBDBM50160909
Synonyms:1-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-2,2,2-trifluoro-ethane-1,1-diol | CHEMBL185346
TypeSmall organic molecule
Emp. Form.C24H17ClF3NO3S
Mol. Mass.491.91
SMILESOC(O)(c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)C(F)(F)F
Structure
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