| Reaction Details |
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 | Report a problem with these data |
| Target | Serpin H1 |
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| Ligand | BDBM50162504 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305934 (CHEMBL833481) |
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| IC50 | 26600±n/a nM |
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| Citation |  Thomson, CA; Atkinson, HM; Ananthanarayanan, VS Identification of small molecule chemical inhibitors of the collagen-specific chaperone Hsp47. J Med Chem48:1680-4 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serpin H1 |
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| Name: | Serpin H1 |
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| Synonyms: | CBP1 | CBP2 | Collagen-binding protein 1 | HSP47 | SERPH_HUMAN | SERPINH1 | SERPINH2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46451.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_305934 |
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| Residue: | 418 |
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| Sequence: | MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
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| BDBM50162504 |
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| n/a |
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| Name | BDBM50162504 |
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| Synonyms: | 4-[1-(4-Fluoro-phenyl)-2-nitro-ethylsulfanyl]-phenylamine | CHEMBL383355 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13FN2O2S |
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| Mol. Mass. | 292.329 |
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| SMILES | Nc1ccc(SC(C[N+]([O-])=O)c2ccc(F)cc2)cc1 |
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| Structure | 
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