| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor 2 |
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| Ligand | BDBM50162898 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_308687 (CHEMBL834127) |
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| Ki | 2400±n/a nM |
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| Citation |  Robarge, MJ; Bom, DC; Tumey, LN; Varga, N; Gleason, E; Silver, D; Song, J; Murphy, SM; Ekema, G; Doucette, C; Hanniford, D; Palmer, M; Pawlowski, G; Danzig, J; Loftus, M; Hunady, K; Sherf, BA; Mays, RW; Stricker-Krongrad, A; Brunden, KR; Harrington, JJ; Bennani, YL Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists. Bioorg Med Chem Lett15:1749-53 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor 2 |
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| Name: | Prostaglandin D2 receptor 2 |
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| Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 43295.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y5Y4 |
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| Residue: | 395 |
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| Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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| BDBM50162898 |
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| n/a |
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| Name | BDBM50162898 |
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| Synonyms: | 2-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-ethanesulfonic acid | CHEMBL362180 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21FN2O5S2 |
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| Mol. Mass. | 452.52 |
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| SMILES | OS(=O)(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 |
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| Structure | 
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