| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM28700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306293 (CHEMBL828585) |
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| IC50 | >50000±n/a nM |
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| Citation |  Liu, K; Xu, L; Berger, JP; Macnaul, KL; Zhou, G; Doebber, TW; Forrest, MJ; Moller, DE; Jones, AB Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia. J Med Chem48:2262-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
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| Type: | Nuclear Receptor |
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| Mol. Mass.: | 57613.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37231 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
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| BDBM28700 |
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| n/a |
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| Name | BDBM28700 |
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| Synonyms: | 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid | 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid | CHEMBL981 | FENOFIBRIC ACID | FIBRICOR | Fenofibrate | LF 153 | alpha-1081 | procetofenic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClO4 |
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| Mol. Mass. | 318.752 |
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| SMILES | CC(C)(Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1)C(O)=O |
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| Structure | 
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