Ki Summary

Reaction Details

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Target

Coagulation factor XIII A chain

Ligand

BDBM50164215

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_304794 (CHEMBL877318)

IC50

170000±n/a nM

Citation

Leung-Toung, R; Tam, TF; Wodzinska, JM; Zhao, Y; Lowrie, J; Simpson, CD; Karimian, K; Spino, M 3-Substituted imidazo[1,2-d][1,2,4]-thiadiazoles: a novel class of factor XIIIa inhibitors. J Med Chem48:2266-9 (2005) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Coagulation factor XIII A chain

Name:

Coagulation factor XIII A chain

Synonyms:

Coagulation factor XIII | F13A | F13A1 | F13A_HUMAN

Type:

PROTEIN

Mol. Mass.:

83261.29

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1475048

Residue:

732

Sequence:

MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVQFTNPLKET
LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
ELDVQIQRRPSM

BDBM50164215

n/a

Name

BDBM50164215

Synonyms:

2-Nitro-N-[6-(3-nitro-pyridin-2-ylamino)-hexyl]-benzenesulfonamide | CHEMBL191254

Type

Small organic molecule

Emp. Form.

C17H21N5O6S

Mol. Mass.

423.444

SMILES

[O-][N+](=O)c1cccnc1NCCCCCCNS(=O)(=O)c1ccccc1[N+]([O-])=O

Structure