| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50164442 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302943 (CHEMBL841778) |
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| Ki | 1412±n/a nM |
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| Citation |  Muccioli, GG; Martin, D; Scriba, GK; Poppitz, W; Poupaert, JH; Wouters, J; Lambert, DM Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation. J Med Chem48:2509-17 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50164442 |
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| n/a |
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| Name | BDBM50164442 |
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| Synonyms: | 5,5-Bis-(4-bromo-phenyl)-3-butyl-2-thioxo-imidazolidin-4-one | 5,5-bis(4-bromophenyl)-3-butyl-2-thioxoimidazolidin-4-one | CHEMBL364312 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18Br2N2OS |
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| Mol. Mass. | 482.232 |
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| SMILES | CCCCN1C(=S)NC(C1=O)(c1ccc(Br)cc1)c1ccc(Br)cc1 |
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| Structure | 
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