| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
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| Ligand | BDBM50165949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303033 (CHEMBL828861) |
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| Ki | >3000±n/a nM |
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| Citation |  Hattori, K; Tanaka, A; Fujii, N; Takasugi, H; Tenda, Y; Tomita, M; Nakazato, S; Nakano, K; Kato, Y; Kono, Y; Murai, H; Sakane, K Discovery of diphenyloxazole and Ndelta-Z-ornithine derivatives as highly potent and selective human prostaglandin EP(4) receptor antagonists. J Med Chem48:3103-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin F2-alpha receptor |
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| Name: | Prostaglandin F2-alpha receptor |
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| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40072.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43088 |
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| Residue: | 359 |
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| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
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| BDBM50165949 |
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| n/a |
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| Name | BDBM50165949 |
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| Synonyms: | C-Phenyl-N-{3-[2-((S)-5-phenyl-4-phenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-benzoyl}-methanesulfonamide | CHEMBL191638 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H32N2O4S |
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| Mol. Mass. | 588.715 |
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| SMILES | O=C(NS(=O)(=O)Cc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:24| |
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| Structure | 
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