| Reaction Details |
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 | Report a problem with these data |
| Target | Pro-cathepsin H |
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| Ligand | BDBM50167289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302985 (CHEMBL876371) |
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| Ki | 1.4±n/a nM |
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| Citation |  Barrett, DG; Deaton, DN; Hassell, AM; McFadyen, RB; Miller, AB; Miller, LR; Payne, JA; Shewchuk, LM; Willard, DH; Wright, LL Acyclic cyanamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett15:3039-43 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pro-cathepsin H |
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| Name: | Pro-cathepsin H |
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| Synonyms: | CATH_HUMAN | CBSP | CPSB | CTSH | Cathepsin H | Cathepsin H heavy chain | Cathepsin H light chain | Cathepsin H mini chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37402.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459870 |
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| Residue: | 335 |
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| Sequence: | MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
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| BDBM50167289 |
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| n/a |
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| Name | BDBM50167289 |
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| Synonyms: | (1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-methylhydrazinecarboxylate | CHEMBL190121 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H21N3O2 |
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| Mol. Mass. | 239.314 |
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| SMILES | C[C@@H](CC1CCCCC1)OC(=O)NN(C)C#N |
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| Structure | 
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