| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
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| Ligand | BDBM50167442 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303341 (CHEMBL840157) |
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| Ki | 29±n/a nM |
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| Citation |  Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: antagonists versus agonists. Bioorg Med Chem Lett15:3020-3 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 3 |
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| Name: | C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41053.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51677 |
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| Residue: | 355 |
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| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
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| BDBM50167442 |
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| n/a |
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| Name | BDBM50167442 |
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| Synonyms: | 1H-Indole-5-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide | CHEMBL190436 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32Cl2N4O |
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| Mol. Mass. | 499.475 |
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| SMILES | Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4[nH]ccc4c3)C2)cc1Cl |
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| Structure | 
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