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TargetEstrogen receptor beta
LigandBDBM50167737
Substrate/Competitorn/a
Meas. Tech.ChEMBL_305778 (CHEMBL827967)
IC50 25±n/a nM
Citation Ji, Q; Gao, J; Wang, J; Yang, C; Hui, X; Yan, X; Wu, X; Xie, Y; Wang, MW Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators. Bioorg Med Chem Lett15:2891-3 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Estrogen receptor beta
Name:Estrogen receptor beta
Synonyms:ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:Protein
Mol. Mass.:59238.43
Organism:Homo sapiens (Human)
Description:Q92731
Residue:530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50167737
n/a
NameBDBM50167737
Synonyms:10-[4-(2-Diethylamino-ethoxy)-benzyl]-10H-benzo[4,5]thieno[3,2-b]indol-7-ol | CHEMBL195991
TypeSmall organic molecule
Emp. Form.C27H28N2O2S
Mol. Mass.444.588
SMILESCCN(CC)CCOc1ccc(Cn2c3ccccc3c3sc4cc(O)ccc4c23)cc1
Structure
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