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TargetDipeptidyl peptidase 2
LigandBDBM12183
Substrate/Competitorn/a
Meas. Tech.ChEMBL_305450 (CHEMBL830125)
IC50>100000±n/a nM
Citation Lu, ILLee, SJTsu, HWu, SYKao, KHChien, CHChang, YYChen, YSCheng, JHChang, CNChen, TWChang, SPChen, XJiaang, WT Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors. Bioorg Med Chem Lett15:3271-5 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dipeptidyl peptidase 2
Name:Dipeptidyl peptidase 2
Synonyms:DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase
Type:Protein
Mol. Mass.:54339.29
Organism:Homo sapiens (Human)
Description:Q9UHL4
Residue:492
Sequence:
MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM12183
n/a
NameBDBM12183
Synonyms:(2S)-1-[(2S)-2-amino-4-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-4-oxobutanoyl]pyrrolidine-2-carbonitrile | CHEMBL362018 | cyanopyrrolidine derivative 6
TypeSmall organic molecule
Emp. Form.C26H29F2N5O2
Mol. Mass.481.5376
SMILESN[C@@H](CC(=O)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@H]1C#N |r|
Structure
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