| Reaction Details |
|---|
 | Report a problem with these data |
| Target | alpha-1,2-Mannosidase |
|---|
| Ligand | BDBM50168997 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302735 (CHEMBL838682) |
|---|
| Ki | 19±n/a nM |
|---|
| Citation |  Fiaux, H; Popowycz, F; Favre, S; Schütz, C; Vogel, P; Gerber-Lemaire, S; Juillerat-Jeanneret, L Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells. J Med Chem48:4237-46 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| alpha-1,2-Mannosidase |
|---|
| Name: | alpha-1,2-Mannosidase |
|---|
| Synonyms: | Alpha-mannosidase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 65344.50 |
|---|
| Organism: | Glycine max |
|---|
| Description: | ChEMBL_32380 |
|---|
| Residue: | 578 |
|---|
| Sequence: | MARGSRSVGSSSSKWRYCNPSYYLKRPKRLALLFIVFVCVSFVFWDRQTLVREHQVEISE
LQKEVTDLKNLVDDLNNKQGGTSGKTDLGRKATKSSKDVLDDPIDIERREKVKEAMLHAW
GSYEKYAWGQDELQPQSKNGVNSFGGLGATLIDSLDTLYIMGLNEQFQKAREWVANSLDF
NKDYEASVFETTIRVVGGLLSAYDLSGDKVFLDKAIEIADRLLPAWNTPTGIPYNIINLS
HGRAHNPSWTGGESILADSGTEQLEFIVLSQRTGDLKYQQKVENVIAQLNKTFPDDGLLP
IYINPHSGAAGYSPITFGAMGDSFYEYLLKVWIQGNKTSSIKHYRDMWEKSMKGLSSLIR
RSTPSSFTYICEKNGGSLTDKMDELACFAPGMIALGSFGYSAADDSQKFLSLAEELAWTC
YNFYQSTPTKLAGENYFFHSGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNI
FQAFEKNSRIESGYVGLKDVNSGVKDNMMQSFFLAETLKYFYLLFSPSSVISLDEWVFNT
EAHPLRIVTRHEEGLVKNLNEKQKPFSRIGGRKEGRSG
|
|
|
|---|
| BDBM50168997 |
|---|
| n/a |
|---|
| Name | BDBM50168997 |
|---|
| Synonyms: | 4-Fluoro-benzoic acid 2-[((2R,3R,4S)-3,4-dihydroxy-pyrrolidin-2-ylmethyl)-amino]-2-phenyl-ethyl ester | CHEMBL190311 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23FN2O4 |
|---|
| Mol. Mass. | 374.406 |
|---|
| SMILES | O[C@H]1CN[C@H](CNC(COC(=O)c2ccc(F)cc2)c2ccccc2)[C@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
