| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-dehydroquinate dehydratase |
|---|
| Ligand | BDBM50170810 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303647 (CHEMBL828995) |
|---|
| pH | 8.2±n/a |
|---|
| Ki | 20000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Sánchez-Sixto, C; Prazeres, VF; Castedo, L; Lamb, H; Hawkins, AR; González-Bello, C Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase. J Med Chem48:4871-81 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-dehydroquinate dehydratase |
|---|
| Name: | 3-dehydroquinate dehydratase |
|---|
| Synonyms: | AROQ_MYCTU | aroD | aroQ |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 15786.25 |
|---|
| Organism: | Mycobacterium tuberculosis |
|---|
| Description: | ChEMBL_766423 |
|---|
| Residue: | 147 |
|---|
| Sequence: | MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLL
DWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSP
IATGVIVGLGIQGYLLALRYLAEHVGT
|
|
|
|---|
| BDBM50170810 |
|---|
| n/a |
|---|
| Name | BDBM50170810 |
|---|
| Synonyms: | (1S,3R,4R)-1,3,4-Trihydroxy-5-hydroxyimino-cyclohexanecarboxylic acid | 3-HYDROXYIMINO QUINIC ACID | CHEMBL363381 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H11NO6 |
|---|
| Mol. Mass. | 205.1653 |
|---|
| SMILES | ONC1C[C@](O)(CC(=O)[C@@H]1O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
