| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM50170861 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303205 (CHEMBL829831) |
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| Ki | 788±n/a nM |
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| Citation |  Durgam, GG; Virag, T; Walker, MD; Tsukahara, R; Yasuda, S; Liliom, K; van Meeteren, LA; Moolenaar, WH; Wilke, N; Siess, W; Tigyi, G; Miller, DD Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem48:4919-30 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM50170861 |
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| n/a |
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| Name | BDBM50170861 |
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| Synonyms: | (1,1-Difluoro-pentadecyl)-phosphonic acid | CHEMBL188859 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H31F2O3P |
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| Mol. Mass. | 328.3754 |
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| SMILES | CCCCCCCCCCCCCCC(F)(F)P(O)(O)=O |
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| Structure | 
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