Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50171464 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_303672 (CHEMBL830433) |
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Ki | 2500±n/a nM |
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Citation | Ohno, M; Miyamoto, M; Hoshi, K; Takeda, T; Yamada, N; Ohtake, A Development of dual-acting benzofurans for thromboxane A2 receptor antagonist and prostacyclin receptor agonist: synthesis, structure-activity relationship, and evaluation of benzofuran derivatives. J Med Chem48:5279-94 (2005) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM50171464 |
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n/a |
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Name | BDBM50171464 |
Synonyms: | CHEMBL187544 | [3-(2,2-Diphenyl-ethylsulfanylmethyl)-benzofuran-7-yloxy]-acetic acid |
Type | Small organic molecule |
Emp. Form. | C25H22O4S |
Mol. Mass. | 418.505 |
SMILES | OC(=O)COc1cccc2c(CSCC(c3ccccc3)c3ccccc3)coc12 |
Structure |
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