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TargetThromboxane A2 receptor
LigandBDBM50171466
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303672 (CHEMBL830433)
Ki 3100±n/a nM
Citation Ohno, MMiyamoto, MHoshi, KTakeda, TYamada, NOhtake, A Development of dual-acting benzofurans for thromboxane A2 receptor antagonist and prostacyclin receptor agonist: synthesis, structure-activity relationship, and evaluation of benzofuran derivatives. J Med Chem48:5279-94 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thromboxane A2 receptor
Name:Thromboxane A2 receptor
Synonyms:Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50171466
n/a
NameBDBM50171466
Synonyms:CHEMBL361939 | {3-[2-(2,2-Diphenyl-ethylsulfanyl)-ethyl]-benzofuran-7-yloxy}-acetic acid
TypeSmall organic molecule
Emp. Form.C26H24O4S
Mol. Mass.432.531
SMILESOC(=O)COc1cccc2c(CCSCC(c3ccccc3)c3ccccc3)coc12
Structure
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