| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin receptor |
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| Ligand | BDBM50171465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303625 (CHEMBL828836) |
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| Ki | 750±n/a nM |
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| Citation |  Ohno, M; Miyamoto, M; Hoshi, K; Takeda, T; Yamada, N; Ohtake, A Development of dual-acting benzofurans for thromboxane A2 receptor antagonist and prostacyclin receptor agonist: synthesis, structure-activity relationship, and evaluation of benzofuran derivatives. J Med Chem48:5279-94 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostacyclin receptor |
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| Name: | Prostacyclin receptor |
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| Synonyms: | PGI receptor | PI2R_HUMAN | PRIPR | PTGIR | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor | Prostanoid IP receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40968.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The membranes prepared from human platelet were used in binding assay. |
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| Residue: | 386 |
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| Sequence: | MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
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| BDBM50171465 |
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| n/a |
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| Name | BDBM50171465 |
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| Synonyms: | CHEMBL190708 | [3-(2-Benzhydrylsulfanyl-ethyl)-2-hydroxymethyl-benzofuran-7-yloxy]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24O5S |
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| Mol. Mass. | 448.531 |
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| SMILES | OCc1oc2c(OCC(O)=O)cccc2c1CCSC(c1ccccc1)c1ccccc1 |
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| Structure | 
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