| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor beta |
|---|
| Ligand | BDBM50171724 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_321253 (CHEMBL880931) |
|---|
| IC50 | 4.3±n/a nM |
|---|
| Citation |  Vu, AT; Cohn, ST; Manas, ES; Harris, HA; Mewshaw, RE ERbeta ligands. Part 4: Synthesis and structure-activity relationships of a series of 2-phenylquinoline derivatives. Bioorg Med Chem Lett15:4520-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor beta |
|---|
| Name: | Estrogen receptor beta |
|---|
| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59238.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92731 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
|
|
|
|---|
| BDBM50171724 |
|---|
| n/a |
|---|
| Name | BDBM50171724 |
|---|
| Synonyms: | 4-Bromo-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-bromo-2-(4-hydroxyphenyl)quinolin-6-ol | CHEMBL198411 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H10BrNO2 |
|---|
| Mol. Mass. | 316.149 |
|---|
| SMILES | Oc1ccc(cc1)-c1cc(Br)c2cc(O)ccc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
