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TargetAldehyde reductase
LigandBDBM16312
Substrate/Competitorn/a
Meas. Tech.ChEMBL_306703
IC50 4000±n/a nM
Citation El-Kabbani OCarbone VDarmanin COka MMitschler APodjarny ASchulze-Briese CChung RP Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. J Med Chem 48:5536-42 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Aldehyde reductase
Name:Aldehyde reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36541.05
Organism:Sus scrofa
Description:ChEMBL_615076
Residue:325
Sequence:
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEAL
TETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
GDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRP
AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK
YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIV
PMLTVDGKRVPRDAGHPLYPFNDPY
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  Blast E-value cutoff:
BDBM16312
n/a
NameBDBM16312
Synonyms:(4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-imidazolidine]-2',5'-dione | CHEMBL266497 | Sorbinil
TypeSmall organic molecule
Emp. Form.C11H9FN2O3
Mol. Mass.236.1992
SMILESFc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1 |r|
Structure
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