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Target1-acyl-sn-glycerol-3-phosphate acyltransferase beta
LigandBDBM50172951
Substrate/Competitorn/a
Meas. Tech.ChEMBL_321473 (CHEMBL880414)
IC50 70.0±n/a nM
Citation Hong, FHollenback, DSinger, JWKlein, P Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta. Bioorg Med Chem Lett15:4703-7 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Name:1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Synonyms:1-acylglycerol-3-phosphate O-acyltransferase beta | AGPAT2 | PLCB_HUMAN
Type:PROTEIN
Mol. Mass.:30924.09
Organism:Homo sapiens (Human)
Description:ChEMBL_321473
Residue:278
Sequence:
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
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  Blast E-value cutoff:
BDBM50172951
n/a
NameBDBM50172951
Synonyms:6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-[1,3,5]triazine-2,4-diamine | CHEMBL195457
TypeSmall organic molecule
Emp. Form.C16H13Cl2N5O
Mol. Mass.362.213
SMILESCOc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Cl)cc2)n1
Structure
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