| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM50173165 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_321910 (CHEMBL883808) |
|---|
| Ki | 4.2±n/a nM |
|---|
| Citation |  Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD Bioisosteric phentolamine analogs as potent alpha-adrenergic antagonists. Bioorg Med Chem Lett15:4691-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48979.91 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08913 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG
PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA
APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD
HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM50173165 |
|---|
| n/a |
|---|
| Name | BDBM50173165 |
|---|
| Synonyms: | CHEMBL194323 | N'-(4,5-Dihydro-oxazol-2-yl)-N-(3-methoxy-phenyl)-N-p-tolyl-hydrazine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19N3O2 |
|---|
| Mol. Mass. | 297.3517 |
|---|
| SMILES | COc1cccc(c1)N(N=C1NCCO1)c1ccc(C)cc1 |w:9.9| |
|---|
| Structure | 
|
|---|
Search and Browse
