| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50173886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_322291 (CHEMBL885046) |
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| IC50 | 37±n/a nM |
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| Citation |  Mai, A; Massa, S; Rotili, D; Pezzi, R; Bottoni, P; Scatena, R; Meraner, J; Brosch, G Exploring the connection unit in the HDAC inhibitor pharmacophore model: novel uracil-based hydroxamates. Bioorg Med Chem Lett15:4656-61 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50173886 |
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| n/a |
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| Name | BDBM50173886 |
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| Synonyms: | 7-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfanyl)-heptanoic acid hydroxyamide | CHEMBL198624 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23N3O3S |
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| Mol. Mass. | 361.459 |
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| SMILES | ONC(=O)CCCCCCSc1nc(Cc2ccccc2)cc(=O)[nH]1 |
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| Structure | 
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