| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50174354 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320830 (CHEMBL871672) |
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| Ki | 1872±n/a nM |
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| Citation |  Armer, RE; Ashton, MR; Boyd, EA; Brennan, CJ; Brookfield, FA; Gazi, L; Gyles, SL; Hay, PA; Hunter, MG; Middlemiss, D; Whittaker, M; Xue, L; Pettipher, R Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2. J Med Chem48:6174-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50174354 |
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| n/a |
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| Name | BDBM50174354 |
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| Synonyms: | CHEMBL373294 | [1-(2,5-Dichloro-benzenesulfonyl)-5-fluoro-2-methyl-1H-indol-3-yl]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12Cl2FNO4S |
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| Mol. Mass. | 416.251 |
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| SMILES | Cc1c(CC(O)=O)c2cc(F)ccc2n1S(=O)(=O)c1cc(Cl)ccc1Cl |
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| Structure | 
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