| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50174419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320933 (CHEMBL882452) |
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| Ki | 3±n/a nM |
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| Citation |  Soulier, JL; Russo, O; Giner, M; Rivail, L; Berthouze, M; Ongeri, S; Maigret, B; Fischmeister, R; Lezoualc'h, F; Sicsic, S; Berque-Bestel, I Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies. J Med Chem48:6220-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 43767.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13639 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
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| BDBM50174419 |
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| n/a |
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| Name | BDBM50174419 |
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| Synonyms: | 1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]-4-{2-[2-(2-{1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]hexahydro-4-pyridinylcarboxamido}ethoxy)ethoxy]ethylcarbamoyl}hexahydropyridine | CHEMBL198271 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H54Cl2N6O10 |
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| Mol. Mass. | 825.776 |
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| SMILES | COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CC1)C(=O)NCCOCCOCCNC(=O)C1CCN(CCOC(=O)c2cc(Cl)c(N)cc2OC)CC1 |
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| Structure | 
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