| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50175213 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_326940 (CHEMBL854328) |
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| Ki | 6400±n/a nM |
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| Citation |  Martina, E; Stiefl, N; Degel, B; Schulz, F; Breuning, A; Schiller, M; Vicik, R; Baumann, K; Ziebuhr, J; Schirmeister, T Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor. Bioorg Med Chem Lett15:5365-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50175213 |
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| n/a |
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| Name | BDBM50175213 |
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| Synonyms: | (2S,3S)-dibenzyl 1-((S)-2-(tert-butoxycarbonyl)-2-(piperidin-1-yl)acetyl)aziridine-2,3-dicarboxylate | CHEMBL198858 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H37N3O7 |
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| Mol. Mass. | 551.6307 |
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| SMILES | CC(C)(C)OC(=O)N[C@@H](N1CCCCC1)C(=O)N1[C@@H]([C@H]1C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 |
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| Structure | 
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