| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50175719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_328881 |
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| EC50 | 14±n/a nM |
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| Citation |  Trabanco AA; Pullan S; Alonso JM; Alvarez RM; Andrés JI; Boeckx I; Fernández J; Gómez A; Iturrino L; Janssens FE; Leenaerts JE; De Lucas AI; Matesanz E; Meert T; Steckler T 4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives, a novel class of selective delta-opioid agonists. Bioorg Med Chem Lett 16:146-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Opioid receptors; mu/kappa/delta |
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| Synonyms: | D-OR-1 | DOR-1 | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50175719 |
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| n/a |
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| Name | BDBM50175719 |
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| Synonyms: | 2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)pyrimidine | CHEMBL202238 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N5 |
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| Mol. Mass. | 395.4995 |
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| SMILES | C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1ncccn1)c1ccccc1 |
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| Structure | 
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