| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50175719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_328877 (CHEMBL859856) |
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| Ki | >4652±n/a nM |
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| Citation |  Trabanco, AA; Pullan, S; Alonso, JM; Alvarez, RM; Andrés, JI; Boeckx, I; Fernández, J; Gómez, A; Iturrino, L; Janssens, FE; Leenaerts, JE; De Lucas, AI; Matesanz, E; Meert, T; Steckler, T 4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives, a novel class of selective delta-opioid agonists. Bioorg Med Chem Lett16:146-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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|
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| BDBM50175719 |
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| n/a |
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| Name | BDBM50175719 |
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| Synonyms: | 2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1-yl)pyrimidine | CHEMBL202238 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N5 |
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| Mol. Mass. | 395.4995 |
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| SMILES | C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1ncccn1)c1ccccc1 |
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| Structure | 
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