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TargetHuman immunodeficiency virus type 1 integrase
LigandBDBM23400
Substrate/Competitorn/a
Meas. Tech.ChEMBL_321311
IC50 10±n/a nM
Citation Barreca MLFerro SRao ADe Luca LZappalà MMonforte AMDebyser ZWitvrouw MChimirri A Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors. J Med Chem 48:7084-8 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 integrase
Name:Human immunodeficiency virus type 1 integrase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:32231.48
Organism:Human immunodeficiency virus 1
Description:ChEMBL_90865
Residue:288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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BDBM23400
n/a
NameBDBM23400
Synonyms:(2Z)-4-(3-benzylphenyl)-2-hydroxy-4-oxobut-2-enoic acid | CHEMBL193759 | CHEMBL19464 | GS-016405
TypeSmall organic molecule
Emp. Form.C17H14O4
Mol. Mass.282.2907
SMILESOC(=O)C(=O)CC(=O)c1cccc(Cc2ccccc2)c1
Structure
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