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TargetHuman immunodeficiency virus type 1 integrase
LigandBDBM50176115
Substrate/Competitorn/a
Meas. Tech.ChEMBL_321433
IC50 17±n/a nM
Citation Barreca MLFerro SRao ADe Luca LZappalà MMonforte AMDebyser ZWitvrouw MChimirri A Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors. J Med Chem 48:7084-8 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 integrase
Name:Human immunodeficiency virus type 1 integrase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:32231.48
Organism:Human immunodeficiency virus 1
Description:ChEMBL_90865
Residue:288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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BDBM50176115
n/a
NameBDBM50176115
Synonyms:(Z)-4-(1-Benzyl-5-methoxy-1H-indol-3-yl)-2-hydroxy-4-oxo-but-2-enoic acid | CHEMBL196689
TypeSmall organic molecule
Emp. Form.C20H17NO5
Mol. Mass.351.3527
SMILESCOc1ccc2n(Cc3ccccc3)cc(C(=O)CC(=O)C(O)=O)c2c1
Structure
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