| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM50176398 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_333862 (CHEMBL864091) |
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| IC50 | 328±n/a nM |
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| Citation |  Durgam, GG; Tsukahara, R; Makarova, N; Walker, MD; Fujiwara, Y; Pigg, KR; Baker, DL; Sardar, VM; Parrill, AL; Tigyi, G; Miller, DD Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. Bioorg Med Chem Lett16:633-40 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM50176398 |
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| n/a |
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| Name | BDBM50176398 |
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| Synonyms: | (S)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosphorothioate | CHEMBL427017 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H41O5PS |
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| Mol. Mass. | 412.565 |
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| SMILES | CCCCCCCCOC[C@@H](COP(O)(O)=S)OCCCCCCCC |
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| Structure | 
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