| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine receptor subunit epsilon |
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| Ligand | BDBM50177174 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_431077 (CHEMBL917782) |
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| IC50 | 125±n/a nM |
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| Citation |  Kapková, P; Heller, E; Unger, M; Folkers, G; Holzgrabe, U Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor. J Med Chem48:7496-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine receptor subunit epsilon |
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| Name: | Acetylcholine receptor subunit epsilon |
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| Synonyms: | ACHE_HUMAN | ACHRE | Acetylcholine receptor protein epsilon chain | CHRNE | Nicotinic acetylcholine receptor alpha-1/beta-1/delta/epsilon |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54686.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_431077 |
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| Residue: | 493 |
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| Sequence: | MARAPLGVLLLLGLLGRGVGKNEELRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNL
ISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQF
GVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTF
AVDNDGKTINKIDIDTEAYTENGEWAIDFCPGVIRRHHGGATDGPGETDVIYSLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLS
VPLLGRFLIFVMVVATLIVMNCVIVLNVSQRTPTTHAMSPRLRHVLLELLPRLLGSPPPP
EAPRAASPPRRASSVGLLLRAEELILKKPRSELVFEGQRHRQGTWTAAFCQSLGAAAPEV
RCCVDAVNFVAESTRDQEATGEEVSDWVRMGNALDNICFWAALVLFSVGSSLIFLGAYFN
RVPDLPYAPCIQP
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| BDBM50177174 |
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| n/a |
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| Name | BDBM50177174 |
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| Synonyms: | 9-amino-5,6,7,8-tetrahydroacridin-4yl)methano | CHEMBL224906 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N2O |
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| Mol. Mass. | 228.2896 |
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| SMILES | Nc1c2CCCCc2nc2c(CO)cccc12 |
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| Structure | 
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