| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 4-aminobutyrate aminotransferase, mitochondrial |
|---|
| Ligand | BDBM26194 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_332431 (CHEMBL867027) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett16:592-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 4-aminobutyrate aminotransferase, mitochondrial |
|---|
| Name: | 4-aminobutyrate aminotransferase, mitochondrial |
|---|
| Synonyms: | (S)-3-amino-2-methylpropionate transaminase | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_HUMAN | Gamma-amino-N-butyrate transaminase | L-AIBAT |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56449.39 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1459248 |
|---|
| Residue: | 500 |
|---|
| Sequence: | MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMK
QLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQ
NASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYR
SKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPS
FDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGG
DNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMM
TGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL
DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVF
RDHHAHLFLNIFSDILADFK
|
|
|
|---|
| BDBM26194 |
|---|
| n/a |
|---|
| Name | BDBM26194 |
|---|
| Synonyms: | 4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | CHEMBL441343 | p-Hydroxybenzoic acid | phenol derivative, 8 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H6O3 |
|---|
| Mol. Mass. | 138.1207 |
|---|
| SMILES | OC(=O)c1ccc(O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
